5th International Conference on
Nanomedicine and Nanotechnology

Nanotechnology is that the direction of matter on an atomic, supramolecular scale and molecular scale. The earliest, boundless characterization of nanotechnology mention to the precise technological goal of absolutely handling atoms and molecules for fabrication of macroscale products, also now attribute to as molecular nanotechnology. Nanotechnology is that the engineering of functional systems at the molecular scale. This covers both current work and ideas that are more advanced.

• Green nanotechnology
• Quantum field model for graphene magnetism
• Nanotubes

Fibers with manometer range are referred as Nano fibers made of different polymers. Nano fibers are synthesized through various methods Electron spinning, Thermal induced phase separation, Drawing Template synthesis, SelfAssembly. Electron spinning Nanotechnology has recently gained importance   because of concept biomimetic Nano fibers for tissue regeneration. The nano fibers scaffolds have been used widely in Tissue engineering, signalling cell alignment, extracellular matrix orientation, and imparting mechanical integrity to the regenerating tissue. Surface fictionalization and bio active factor delivery within these Nano fibrous scaffolds to enhance Bone regeneration

• Osteogenesis
• Angiogenesis
• Cellular response
• Tissue regeneration
• Scaffolding
• Transplantation

 Materials organised into small scale are often referred to as Nano material in the range of 1- 100 nanometres having unique Optical, magnetic, electrical, and other properties. The size of Nano material is valuable in product development, Drug delivery, size, shape. Nano material are synthesized by Bottom up and Top down approaches. Nano material can be seen everywhere in nature. Biomedical and pharmaceutical industry mainly focus on metal base Nano material they are used in healthcare such as contrast dyes that work with MRI and scanning devices for Diagnostic purposes.

• Nano scale particles
• Synthesis methods
• Nano Enzymes
• Natural Nanomaterials
• Metal based nanomaterials

Materials science is a syncretic discipline hybridizing ceramics, metallurgy, chemistry, and solid-state physics. It is the primary example of a replacement academic discipline emerging by fusion instead of fission. This paradigm is used to advance understanding in a variety of research areas, including nanotechnology metallurgy and biomaterials. Materials science is additionally a crucial a part of forensic engineering and failure analysis – investigating materials, products, structures, or components which fail or don't function as intended, causing personal injury or damage to property. Such investigations are key to understanding, for example, the causes of various aviation incidents and accidents.

• Metal-based nano particles
• Metallurgy and materials science
• Materials for energy applications
• Fundamentals of material science
• Polymeric materials

Molecular nanotechnology (MNT) is a technology to establish on the prospective to construction to compound, atomic identifications by consider of machine-synthesis. This is distinct from Nano scale materials are a technology based on the ability to build structures to complex, atomic identifications by means of machine-synthesis. If the consumption in measurements of electronic device continues at its present exponential place, the measurement of entire gadgets will approach that of molecules within a few decades. However, well before this happens, both the physics upon which electronic gadgets are based and the manufacturing procedures used to produce them will have to change dramatically.

• Molecular assembler
• Molecular engineering
• Supramolecular assembly
• Self-assembled monolayer
• Molecular scale electronics
• Molecular communication

 This discipline helps to point the merger of scientific research with various fields of nanotechnology. Concepts that are enhanced through nanobiology include the topics like nanoparticles, nanodevices  (such as biological machines) and nanoscale phenomena that happens within the discipline of nanotechnology.  This technical approach to biology allows scientists to imagine and make systems which will be used for scientific research.

• Nanobiosensor
• Biological nanonetworks
• Bioluminescent magnetic nanoparticles
• Surface modified polystyrene nanoparticles
• Target specific drug delivery

Nanoparticle drug delivery systems are engineered technologies that use nanoparticles for the targeted delivery and controlled release of therapeutic agents. Each material has uniquely tunable properties and thus can be selectively designed for specific applications. The National Institute of Biomedical Imaging and Bioengineering has issued the following prospects for future research in nanoparticle drug delivery systems like crossing the blood-brain barrier (BBB) in brain diseases and disorders, enhancing targeted intracellular delivery to ensure the treatments reach the correct structures inside cells, combining diagnosis and treatment. The modern form of a drug delivery system should minimize side-effects and reduce both dosage and dosage frequency.

• Nano pharmaceuticals
• Medical nanotechnology in cancer therapy
• Nanotechnology in cardiovascular medicine
• Nano-anti-viral drugs
• Gene therapy

Quantum nanoscience is that the basic research area at the intersection of nanoscale science and quantum science that makes the understanding that permits development of nanotechnologies. With the growing work toward realization of quantum computing, quantum has taken on new meaning that describes the consequences at this scale. Current quantum refers to the quantum mechanical phenomena of superposition, entanglement and quantum coherence that are engineered rather than naturally occurring phenomena. It uses quantum physics to explore and utilize coherent quantum effects in engineered nanostructures. Coherence is that the property of a quantum system that permits to predict its evolution in time once it's been prepared during a superposition of various quantum states.

• Nanofabrication
• Nanolithography
• Nanometrology
• Nanofluidics

DNA Nanotechnology is occasionally split into two overlapping subfields they are structural DNA nanotechnology and dynamic DNA nanotechnology. Some tissues, such as nucleic acid Nano mechanical devices, combine features of both the structural and dynamic subfields.  These PNC's belong to the classification of multi-phase systems that consume nearly 95% of plastics production. Polymer Nano science is the research and implementation of Nano science to polymer-nanoparticle matrices, where nanoparticles are those with at least one measurement is of less than 100 nm. Carbon nanotubes, gold particles and synthetic polymers are utilized for this determination. 

• DNA computation
• Structural DNA nanotechnology
• Dynamic DNA nanotechnology

Nano biosensors , Nano probes are a new class of bio sensing and imaging Nano devices and imaging devices that allow for analytical measurements in individual living cells. The application of nanotechnology to biosensor design and fabrication promises to progress the diagnostics and therapy at the molecular and cellular level. The prospective for monitoring  in vivo biological processes within single living cell, will considerably improve our understanding of cellular function, leading to mutative cell biology.

• Micro dialysis
• In vitro diagnostic
• Theragnostic
• Targeted Drug delivery
• Optical fibre

Imaging probes substantially improves the specificity and sensitivity of diagnostic imaging by allowing the non-invasive and quantitative detection of specific biomolecules in living subjects. Molecular imaging probes consist of a nano particle that has been fictionalized with a targeting agent Interest in the use of nanoparticles stems from their ability to provide improved contrast compared with more traditional contrast agents and the ability to control their Pharmacokinetics through variations of their size, surface properties, and shape.

• Clinical oncology
• Cancer and tumour
• Pharmacokinetic evaluation
• Neurodegenerative diseases

Nano particles are ultra-fine particles whose diameters range 1-100 nano meters in 3 dimensions. Nano particles are made of natural or synthetic polymers carrying drug or antigens. Nano particles have wide applications in cancer therapy , intracellular, vaccine adjustment, DNA delivery, ocular delivery. Conjugation of cell specific ligands to the surface of manometer range drug carriers potentially increase delivery of a therapeutic agent to a desired specific site, while decreasing unwanted delivery to other sites this is often described as active targeting. Nano particles are in conjugation with targeting ligands which possess  selective  binding ability  this technique is referred as Functionalising nanoparticles  properties and characteristics of alters through surface modification which plays a major role in the field of medicine. Fictionalizing the nanoparticles specifically to enhance bio imaging quality functional images is required with proper differentiation which can be used in molecular therapy.

• Cellular epitopes
• Bi specific antibodies
• Anti-tumoral therapy

Nanotechnology has vast applications in field of dentistry. Nanotechnology concept-based design is mimics some of the mechanical and structural properties of existing tissue and promote bio integration. The development of Nano dentistry promotes oral health using nano material and biotechnology methods. Oral fluid Nano sensor test this technology detects salivary bio markers for oral cancer,  researchers developed Nano-toothbrush, by using Nano gold or Nano silver colloidal particles between toothbrush bristles  Implantable devices, Nano robotic local anaesthetics, Nano robots can deal with Dentin Hypersensitivity, Dentifrice are Nano robots joined into dentifrices and mouthwashes to clean organic residues by moving throughout the gingival tissue, orthodontic Nano robots manipulate the periodontal tissue allowing painless teeth straightening in minutes and several other applications like dentition denaturalization, permanent cure  of hypersensitivity, Nano solutions used in orthodontics brackets etc.

• Nanofillers
• Dentifrobots
• Dentin Hypersensitivity

Conversion of Mechanical or Thermal energy produced by small scale physical change into electricity called piezoelectricity is known as Nano generators. Mechanical energy is harvested and converted into power source in this method. Nano generators mainly use three type paths including triboelectric, piezoelectric and pyro electric. Nano generators have added a new magnitude to the principles of converting mechanical energy into electrical energy using piezoelectric and triboelectric effects. Power generating artificial skin is one of the applications of Nano biosystems 

• Self-powered Nano system
• Piezoelectric electric city
• Nanogenerators
• Photovoltaics

The promise of regenerativemedicine is truly remarkable. Regenerative medicine is a new branch of medicine that attempts to change the course of chronic disease, in many instances regenerating failing organ systems lost due to age, disease, damage, or congenital defects. The area is rapidly becoming one of the most promising treatment options for patients suffering from tissue failure.

Nanomedicineformulations aim to improve the biodistribution and the target site accumulation of systemically administered (chemo) therapeutic agents. Many different types of nanomedicines have been evaluated over the years, including for instance liposomes, polymers, micelles and antibodies, and a significant amount of evidence has been obtained showing that these submicrometric-sized carrier materials are able to improve the balance between the efficacy and the toxicity of therapeutic interventions. Besides for therapeutic purposes, nanomedicine formulations have in recent years also been increasingly employed for imaging applications. Moreover, paralleled by advances in chemistry, biology, pharmacy, nanotechnology, medicine and imaging, several different systems have been developed in the last decade in which disease diagnosis and therapy are combined. These so-called (nano)theragnostic contain both a drug and an imaging agent within a single formulation, and they can be used for various purposes. In this Account, we summarize several exemplary efforts in this regard, and we show that theragnostic nanomedicines are highly suitable systems for monitoring drug delivery, drug release and drug efficacy. The (pre)clinically most relevant applications theragnostic nanomedicines relate to their use for validating and optimizing the properties of drug delivery systems, and to their ability to be used for pre-screening patients and enabling personalized medicine

Biopharmaceutics is defined as the study of factors influencing the rate and amount of drug that reaches the systemic circulation and the use of this information to optimise the therapeutic efficacy of the drug products. The process of movement of drug from its site of administration to the systemic circulation is called as absorption. The concentration of drug in plasma and hence the onset of action, and the intensity and duration of response depend upon the bioavailability of drug from its dosage form. Bioavailability is defined as the rate and extent (amount) of drug absorption. Biologic Drugs, or biologic response modifiers, are medications genetically engineered from a living organism, such as a virus, gene, or protein, to simulate the body’s natural response to infection and disease. Biologics target proteins, cells and pathways responsible for the symptoms and damage of rheumatoid arthritis other types of inflammatory arthritis. Biologic response modifiers (biologics for short) are drugs that are genetically engineered from a living organism, such as a virus, gene, or protein, to simulate the body’s natural response to infection and disease.

Maintained medication conveyance has the planned to enhance the treatment and avoidance of numerous conditions and ailments that harass the female conceptive tract. Be that as it may, accomplishing compelling, remedial conveyance in the vaginal tract is trying because of vaginal physiology. To conquer these issues, we are rising Nano medicine and novel conveyance vehicles that can give managed discharge (enhancing adequacy) and convey tranquilizes consistently to the objective surface.

•        Breast cancer

•        Cervical and ovarian cancers

•        Global Health Challenges for Paediatric and Geriatric

•        HIV/AIDS and STDs/STIs: Vaccines research and development

•        Nanomedicine for Gastrointestinal tract Diseases

To maximize knowledge of the current researcher on developing drug delivery via Pharmaceutical formulation,  Smart Drug Delivery conference themed quality topics on Drug Targeting, Drug Designing, Drug evaluation, Drug Delivery and Therapeutics,  polymers, Dendrimer a versatile polymer in drug delivery are a uniquely architect session to play an important role in the fields of nanotechnology, pharmaceutical and medicinalchemistry.

Major drugs driving growth of the overall smart drug delivery market include Angiomax, Copaxone, Forteo , Sandostatin,Velcade, Victoza and Zoladex.

•        Insitu Drug Delivery

•        Lymphoid Drug Delivery System

•        Hydrogel in Drug Delivery

•        Sonophoresis Drug Delivery System

•        Micelle Drug Delivery

•        Trans mucosal Drug Delivery Systems

•        Nano Biosensors

Nanotoxicology refers to the study of the interactions of nanostructures with biological systems with an emphasis on identifying the relationship between the physical and chemical properties of nanostructures and induction of toxic biological responses. A complete understanding of the relationship between unique properties of nanostructures and in vivo and in vitro behaviours will provide a strong basis for assessing toxic responses. Studies in animal models will identify the organs of interest, in turn leading to identification of the best cell types for in vitro cytotoxicity studies to further enhance our understanding of how these cells molecularly respond to the nanostructures. Toxicologic tests and the resulting database would provide information for material safety data sheets for nanoparticles as well as abasis for risk assessment and management.

•        Oxidative stress

•        Cytotoxicity

•        Genotoxicity